Bax Protein Expression Correlates With Radiation‐induced Apoptosis In Radiation Therapy For Cervical Carcinoma

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PROTEOMIC ANALYSIS OF DNA DAMAGE INDUCED STRESS SIGNALING

The expression of S100A6 was investigated in stage I non-small cell lung cancer by immunohistochemistry using tissue microarrays. S100A6 was found overexpressed in cancer cells, and S100A6 expression correlated with wt p53 expression. S100A6 expression also correlated with patient survival in a subset of the cohort.

放射線治療におけるがん関連遺伝子の発現と照射効果予測

1. Ohno T,Nakano T,Niibe Y,Tsujii H,Oka K. Bax protein expression correlates with radiation-induced apoptosis in radiation therapy for cervical car-cinoma. Cancer 1998;83:103-110. 2.大野達也,中野隆史,岡 邦行,他.生検材料を用い た重粒子線治療の照射効果に関する分子病理学的研 究.

Clinical Medicine Insights: Ear, Nose and Throat

can be salvaged with surgery or radiation therapy, the majority are incurable, and are treated palliatively with systemic therapy. In the setting of first line therapy for recurrent/metastatic HNSCC, the EXTREME trial provided level 1 evidence that cetuximab improves overall survival when combined with cisplatinum and 5 FU.