Risk Assessment Model For First‐cycle Chemotherapy‐induced Neutropenia In Patients With Solid Tumours
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Current management of chemotherapy-induced neutropenia in
consensus nomogram for FN risk assessment has been established. (3) Different assessment tools [e.g., Multinational Association for Supportive Care in Cancer (MASCC), the Clinical Index of Stable Febrile Neutropenia (CISNE) score model, and other tools] have been suggested to help stratify the risk of complications in patients with FN.
STUDY PROTOCOL Open Access Febrile neutropenia (FN
patients receiving common myelosuppressive chemotherapy regimens for metastatic solid tumours, most frequently during the first cycle (23% to 36%) [ 4]. Granulocyte colony-stimulating factors (G-CSFs) can be used prophylac-tically to reduce the risk, severity and duration of FN, and as an adjunct to support the delivery of dose-dense (increased
Neutropenia Risk Assessment Prior to Chemapy
Feb 01, 2021 medical record prior to the first cycle of intravenous chemapy Numerator Number of patients who had an FN risk assessment documented in the medical record prior to the first cycle of intravenous chemapy. Denominator Number of patients 18 years of age or older with a solid malignant tumor or lymphoma receiving the first cycle of intravenous chemapy.
Corporate Presentation th Annual J.P. Morgan Healthcare
If Grade 4 neutropenia (ANC < 0.5x109 cells/L) is not treated, patients could die in first cycle of chemotherapy CIN #1 reason for FN, hospitalization, sepsis, mortality and chemotherapy disruption1 Slight Changes in Dosing or Delivery Can Have A Devastating Impact on Survival2 G-CSF monotherapy is suboptimal and leaves a significant clinical gap
CHAPTER 133 REFERENCES
tive model for risk of developing febrile neutropenia in the first cycle of che-motherapy among elderly patients with breast, lung, colorectal and prostate cancer. Supp Care Cancer 2011;19:333 341. 32. Chia VM, Page GH, Rodriguez R, et al. Chronic comorbid conditions as-sociated with risk of febrile neutropenia in breast cancer patients