Pulse Pressure Amplification And Risk Of Cardiovascular Disease

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Blood Pressure and Cognitive Function: The Role of Central

cognitive performance not predicted by brachial blood pressure. Keywords blood pressure, hypertension, central pressure, pulse-pressure amplification, cognition, brain, dementia, cognitive ability, cognitive neuroscience, nervous system disorders Received 12/10/12; Revision accepted 4/7/13 The importance of vascular risk factors in the develop

ENG IEM Mobil-O-Graph PWA Information sheet nephrology

Aortic to brachial pulse pressure amplification as functional marker and predictor of renal function loss in chronic kidney disease. Wassertheurer et al. The Journal of Clinical Hypertension. April 2014 Aortic pulse wave velocity predicts mortality in chronic kidney disease stages 2-4. Baumann M, Wassertheurer et al.; Journal of Hypertension.

Hypertension in Older People: Part 1

Stiffening disease, an age-related degeneration of the elastic elements of the thoracic aorta, is associated with a widening of brachial pulse pressure. Brachial pulse pressure predicts future cardiovascular dis-ease events. However, pressure wave amplification produces higher brachial than aortic pressures and,

SQUATTING AMPLIFIES PULSE PRESSURE INCREASE WITH DISEASE

Oct 31, 2007 Pulse pressure and type 1 diabetes duration arly vascular aging was reported in type 1 diabetes (T1DM) (1-5). Arterial pulse pressure (PP), a surrogate marker of artery stiffness, is an independent cardiovascular disease (CVD) risk factor in T1DM patients (6), as in non-diabetic (7-9) or T2DM (10,11) individuals.

Research status of pulse pressure

Nov 07, 2019 Abstract: Pulse pressure is the result of the periodicity of cardiac contraction and the nature of arterial circulation. Pulse pressure is affected by age, gender, height, heart rate, cholesterol, diabetes, hypertension, homocysteine, pulse pressure amplification,

Managing Cardiovascular Disease and Hypertension Using

Due to arterial pressure amplification, central blood pressure is lower than at peripheral locations such as the brachial artery, where blood pressure is traditionally measured. Importantly, it is not possible to estimate the central blood pressure from the brachial BP. Managing Cardiovascular Disease and Hypertension Using Central Blood Pressure

Arterial Stiffness and Coronary Artery Disease

reflection (AIx, brachial pressure amplification) and central pulse pressure in 2,232 patients and correlated these measures with major cardiovascular outcomes including myocardial infarction, stroke, unstable angina and heart failure. The multivariate analysis showed that patients with higher PWV values had 48% higher risk of cardiovascular

Central hemodynamics and prediction of cardiovascular events

pressure pulse amplification of a varying degree when moving from the aorta to the periphery Central (aortic, carotid) pressures are pathophysiologically more relevant than peripheral pressures for the pathogenesis of cardiovascular disease Direct wave Reflected wave Central pressures and Augmentation index

Low Ankle Brachial Indices Reflect Left Ventricular Systolic

Peripheral artery disease (PAD) is a growing health concern in the United States due its rising prevalence, its impact on functional disability and increased risk for cardiovascular and cerebrovascular events. A recent review by Basgoz et al. [1] summarized the importance of screening for PAD and its association with coronary artery disease (CAD).

Hypertensive response to exercise: mechanisms and clinical

cardiovascular outcomes (fatal or non-fatal myocardial in-farction, stroke, or development of coronary artery disease) Fig. 1 Pathophysiological pathways through which exercise pulse pressure amplification may contribute to the development of left ventricular longitudinal dysfunction in individuals with an

Arterial stiffness in diabetes and the metabolic syndrome: a

increased cardiovascular disease risk observed in these conditions. Arterial stiffness can be estimated by quantify-ing pulse pressure but is better described by distensibility and compliance coefficients, pulse wave velocity and wave reflection. The most common non-invasive methodologies used to quantify these estimates of arterial stiffness (e.g.

Arterial wave reflection and subclinical atherosclerosis in

mented pressure (difference between second and first systolic shoulder) ex-pressed as a percentage of central pulse pressure. Reflection magnitude was cal-culated as (reflected wave amplitude/ forward wave amplitude) x 100 and pulse pressure amplification as the ra-dial pulse pressure divided by the aortic pulse pressure. All measurements were

Opiate exposure increases arterial stiffness, advances

vascular age and is an independent cardiovascular risk relative risk of cardiovascular disease of 2.2 (95% C.I. Peripheral-Central Pulse Pressure Amplification

Hemodynamics - citeseerx.ist.psu.edu

cardiovascular disease risk factors in adults and associates with elevated cardiovascular disease risk in healthy persons.4 6 Childhood cardiovascular disease risk factors, such as elevated blood pressure, are suggested to predict carotid artery stiffness in adulthood. 2 In adults, arterial stiffening has also been associ-

Rapid Communication

Key Words: smoking arterial stiffness pulse pressure amplification S moking is a major risk factor in the development and progression of cardiovascular disease. 1 Despite extensive

Pulse Pressure and Target Organ Damage - IntechOpen

Pulse Pressure and Target Organ Damage Adel Berbari and Abdo Jurjus American University of Beirut, Lebanon 1. Introduction Hypertension remains the major risk for cardiovascular disease, stroke and end-stage nephropathy. Hypertension is traditionally defined in terms of elevated systolic and or diastolic blood pressure (BP).

Blood Pressure Measurement in Atrial Fibrillation: Is there a

the former in predicting cardiovascular risk. Moreover, recent studies suggest that the pulse pressure amplification may offer additional prognostic value beyond that of central and peripheral pulse pressure alone [9,10]. Non-Invasive Central Blood Pressure Measurement and Pulse Pressure Amplification

i c a l r& E xpeime C l in tal Clinical & Experimental f o l

significantly greater for men than for women. Expected increase of odds for the pulse pressure amplitude increase with 0.1 is obtained. Conclusions: The studies prove that pulse pressure amplitude is a marker of myocardial infarction risk. When the pulse pressure amplitude is used for risk level evaluation at least sex should be taken into account.

Pulse Pressure in Clinical Practice - Healthcare Bulletin

Cardiovascular risk assessment using pulse pressure in the first national health and nutrition examination survey (NHANES I). Hypertension. 2001 Oct;38(4):793-7. Franklin SS, Larson MG, Khan SA, Wong ND, Leip EP, Kannel WB, Levy D: Does the relation of blood pressure to coronary heart disease risk change with aging? The Framingham Heart Study.

LIFESTYLE CONTRIBUTORS TO CARDIOVASCULAR DISEASE RISK

Aortic stiffness is an independent risk factor that has prognostic value regarding future cardiovascular disease (CVD) events such as myocardial infarction, strokes, and heart failure. Although death rates due to coronary heart disease have declined in recent years, the leading global killer remains CVD and prevalence is still high.

Angiology From Arterial to Cardiac Dysfunction The Author(s

artery disease (CAD). Briefly, cross-sectional aortic distensi-bility, an index of local arterial stiffness, was lower at baseline in patients with CAD who developed cardiovascular (CV) events. This finding is in agreement with the concept that increased arterial stiffness is a CV risk factor. Moreover, a

RESEARCH ARTICLE Elevated Pulse Pressure is Associated with

cardiovascular risk factor in other populations. Hence, we hypothesized that pulse pressure, unlike other blood pressure parameters, is independently associated with markers of hemolytic anemia and cardiovascular risk in sickle cell disease. We analyzed the correlates of pulse pressure in patients (n 5 661) enrolled in a

Body composition is a strong predictor of local carotid

ness index, indicate stiffer vessels [11]. Because of pulse pressure amplification in young subjects, with a higher blood pressure in the peripheral arteries, it is of import-ance to use the local blood pressure from the same site as the relative diameter change is measured. The gold standard is to use the local blood pressure in the calcula-

Correspondence - Pennsylvania State University

Moreover, upper-limb pulse pressure amplification is suggested to be a new biomarker of cardiovascular disease 3 ; cardio- vascular risk increases as pulse pressure amplification decreases.

Arterial Destiffening with Weight Loss in Overweight and

A. Cardiovascular disease mortality and morbidity 5 I.6 Pulse pressure amplification 21 individuals are at a greater risk for suffering from chronic diseases

Beneficios que ofrece dejar de fumar

Mahmud A, Feely J. Effect of smoking on arterial stiffness and pulse pressure amplification.€Hypertension. 2003;41(1):183-187. McEvoy JW, et al. Cigarette smoking and cardiovascular events: Role of inflammation and subclinical atherosclerosis from the multiethnic study of

Cardiovascular Risk Factors and Disease Characteristics Are

May 25, 2017 cycline use (p = 0.02) to decreased peripheral pulse pressure. Conclusion. Traditional cardiovascular risk factors and disease characteristics are consistently associated with vascular hemodynamic alterations in RA. The relative effect of arterial stiffness, wave reflection, and pressure pulsatility on CVD risk in RA needs further study.

The effect of antihypertensive drugs on arterial stiffness

patients at lower cardiovascular risk than in patients at higher cardiovascular risk [24]. Finally, a meta-regression analysis revealed that aortic pulse wave velocity is a stronger determinant of prognosis in younger patients with end-stage renal disease, while the predictive value of aortic pulse wave velocity is independent of age in

cSy n a nd u rom Journal of Metabolic Syndrome

risk score as well as peripheral and central blood pressure, cardiac end systolic pressure, and its direct relation to pulse pressure amplification highlighted its potential impact on pathogenesis of metabolic syndrome and arterial stiffness. *Corresponding author: Ali Reza Khoshdel, Department of Epidemiology,

Effect of Smoking on Arterial Stiffness and Pulse Pressure

Key Words: smoking arterial stiffness pulse pressure amplification Smoking is a major risk factor in the development and progression of cardiovascular disease.1 Despite extensive research, the pathophysiological mechanisms that are respon-sible for smoking-related vascular damage have not been elucidated.

Atrial fibrillation is associated with increased central

pressure pBP) compared to the aorta (central blood pressure cBP).2 Arterial stiffness (AS) and cBP are increasingly recognized important risk factors for cardiovascular disease,3 6 but they have rarely been studiedinAFpatients(Figure1). Beta blockers (BBs) are the first-choice drugs for long-term rate

Health Benefits of Quitting Smoking Over Time

Mahmud A, Feely J. Effect of smoking on arterial stiffness and pulse pressure amplification.€Hypertension. 2003;41(1):183-187. McEvoy JW, et al. Cigarette smoking and cardiovascular events: Role of inflammation and subclinical atherosclerosis from the multiethnic study of

Pressure Amplification Explains Why Pulse Pressure Is

Abstract Pulse pressure rather than diastolic pressure is the best predictor of coronary heart disease risk in older subjects, but the converse is true in younger subjects. We hypothesized that this disparity results from an age-related difference in pressure amplification from the aorta to brachial artery. Data from 212 subjects age 50 years

Household air pollution and measures of blood pressure

pulse pressure amplification (−0.007 (P=0.04)). among younger women, the associations were inconsistent in the direction of effect and not statistically significant. increased PM 2.5 exposure was associated with no difference in pulse wave velocity and modestly higher augmentation index though the ci included zero (1.1%; 3

State of the Art Central Blood Pressure Measurement January

cardiovascular risk in selected patient groups than brachial pressure. Therefore, it seems likely that the assessment of central pressure will improve the identification and management of patients with elevated cardiovascular risk. The term amplification [ provides nomenclature for discussion of the relative under- or -over-

Tamara Horwich, MD, MS

disease in women, cardiac rehabilitation, treating patients with heart failure, and performing and interpreting echocardiograms. Dr. Horwich's main research interests include studying obesity, body composition and cardiovascular disease, as well as risk factors and novel therapies for patients with heart disease, with a focus on women.

Journal of AIDS & Clinical Research

Arterial wave reflections; Pulse pressure amplification; Cardiovascular disease risk factors; Plasma vitamin D Introduction Combined antiretroviral therapy has led to a substantial decline in AIDS-related morbidity and mortality [1,2]. Mortality and overall incidence of opportunistic infections declined markedly in 1996 and

Chapter 24. Vascular Aging and Cardiovascular Disease

increase in pulse pressure after 50 years of age, and a higher systolic and pulse pressure amplification has been reported after menopause, increasing significantly CV mortality. The impact of hormones on these findings is an ongoing debate [19 21].