Comparative Analysis Of Regulatory Transcription Factors In Schizosaccharomyces Pombe And Budding Yeasts

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Critical Review Molecular Basis of the Regulation

budding yeast Saccharomyces cerevisiae and multicellular eukaryotes (3 6). This review focuses on a description of iron-responsive regulators in Schizosaccharomyces pombe, Aspergillus nidulans, A. fumigatus, Candida albicans, and Cryptococcus neoformans, first in a context where iron levels

Molecular Microbiology First published online 5 July 2012

homologues from the yeasts S. pombe (S.p.) and S. cerevisiae (S.c.). Conserved features are indicated with black bars. Amino acid substitutions resulting from the mutations identified in rho-1 mutant alleles (9-1) and (10-1) are highlighted in blue and red respectively. C. Wild type and mutants were grown for 24 h at room temperature on

Microbial Genetics - WordPress.com

genomes, comparative genomics, The yeasts S. cerevisiae, and S. pombe are important model organisms in science, since they are simple eukaryotes that can be grown rapidly in large numbers and are Transcription (RNA polymerase, promoters, terminators, transcription factors)

Biochimica et Biophysica Acta - CiteSeerX

Major Conclusions: Comparative genomic approaches, pioneered in budding yeasts, have resulted in dramatic improvements in our understanding of the function of both genes and regulatory sequences. Analogous studies in other systems, including humans, demonstrate the ubiquity of comparative genomic approaches.

Global transcriptional responses of fission and budding

humans [3,4]. The fission yeast Schizosaccharomyces pombe provides a complementary model of copper homeostasis. It is estimated that S. pombe diverged from S. cerevisiae approxi-mately 0.3 to 1.1 billion years ago [5], and many gene sequences are as distantly related between the two yeasts as to their human homologs. A comparison between budding

GC-Rich DNA Elements Enable Replication Origin Activity in

studied origin model is the fission yeast Schizosaccharomyces pombe where longer (500 bp to 1 kb) stretches of A/T DNA are stochastically recognized by a domain of nine AT-hooks on the N-terminus of one of the ORC subunits Orc4 [21 23]. Replication origins in metazoans have not been delineated to the same extent as in yeast.

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2/10/2012  55 Prw1 in Schizosaccharomyces pombe , are not essential. In contrast to eukaryotes, 101 of the cell cycle by inhibiting E2F transcription factors (25, 42). Interestingly, By comparative phenotypic analysis of msl1 mutants with ras1 and the

Pleiotropic Roles of the Msi1-Like Protein Msl1 in

1 phase of the cell cycle by inhibiting E2F transcription factors (25, 42). Interestingly, the corepressor activity of Msi1/ Cac3 for pRB does not require Cac2, indicating that CAF-1 is not involvedinthisprocess.In Arabidopsis,theMSI1proteininteracts in vivo with the pRB homolog retinoblastoma-related 1 (Rbr1) and