More On Adjuvant Therapy In Resected Melanoma

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Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or

therapy and combination therapy in several coun-tries worldwide for the treatment of patients with metastatic melanoma on the basis of the results of phase 3 randomized trials. 1-4 In 2015, the Food and Drug Administration approved ipilimumab as adjuvant therapy in patients with resected stage III melanoma on the basis of recurrence-free sur-

Adjuvant immunotherapy for melanoma

a guide for establishing effective adjuvant therapy strategies in pa-tients with melanoma. The selection of patients who would benefit from adjuvant therapy must be individualized and should take into account multiple factors, including (1) the risk of recurrence, (2) the efficacy of adjuvant therapy in reducing this risk, (3) the toxicity of

Systematic Review of Systemic Adjuvant Therapy for Patients

The authors examined the role of systemic adjuvant therapy in patients with high-risk, resected, primary melanoma. Outcomes of interest included overall survival, disease-free survival, adverse effects, and quality of life. A systematic review of the literature was conducted to locate randomized controlled trials,

Systemic Therapy for Melanoma: ASCO Guideline

What adjuvant systemic therapy options, alone or in combination, have demonstrated clinical benefit in adults with resected (stage II, III, IV) cutaneous melanoma ? Are there subpopulations of patients

Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or

has also been approved as adjuvant therapy for melanoma on the basis of recur- mab group more than 100 days after treatment. mab as adjuvant therapy in patients with resected

Adjuvant Pembrolizumab versus Placebo in Resected Stage III

Apr 15, 2018 As adjuvant therapy for high-risk stage III melanoma, 200 mg of pembrolizumab ad- ministered every 3 weeks for up to 1 year resulted in significantly longer recurrence- free survival than placebo