Experimental Obstruction Of Renal Veins

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Dissociation of glomerular filtration and renal blood flow in

glomerular filtration rate (GFR), from 45 4to 25 2mI/mm, and renal blood flow (RBF), from 268 22 to 161 19 mI/mm, decreased simultaneously. A rise in diuresis and urinary solute excretion oc-curred. Morphological and functional studies excluded a major role for tubular leakage or obstruction. An attempt was made to prevent the


Blood supply to the kidneys is provided by the renal arteries, which are large branches of the aorta (Schummer et al, 1979; Wenzel, 1999). The renal veins return blood directly into the caudal vena cava (Wenzel, 1999). The ureters are paired, tube-like structures that collect urine from the ipsilateral renal pelvis and convey it to the urinary

Acute renal venous obstruction is more detrimental to the

CALL FOR PAPERS Renal Hemodynamics Acute renal venous obstruction is more detrimental to the kidney than arterial occlusion: implication for murine models of acute kidney injury Xiang Li,1,5 Manchang Liu,1 Djahida Bedja,2 Christopher Thoburn,3 Kathleen Gabrielson,2 Lorraine Racusen,4 and Hamid Rabb1

The Effect of the Partial Obstruction Site of the Renal Vein

partially occluding the left renal vein medial to the in-sertion of the left internal spermatic vein. Early reports on the effects of unilateral, experimental varicocele involved the use of monkeys and dogs to demonstrate bilateral in-creases in testicular temperature, morphological damage to testes, and decreases in ejaculated sperm concentrations

Ureteropelvic Junction Obstruction by an Accessory Renal

aberrant renal vasculature demonstrated elevated renin levels in the ipsilateral renal vein or peripheral veins; in several instances, surgical correction of the obstruction resulted in normalization of renin levels and resolution of hypertension [4-6]. In contrast, there have also been several reported cases

Experimental models of renal dysfunction in female rats

experimental studies on the obstruction of the renal vein in dogs and mice, as well as its effects on renal function and histology were performed11, showing early alterations in both situations, represented by significant proteinuria, hemorrhagic infarction and congestion the renal parenchyma. Some changes would be

Effect of Endothelin-A Receptor Blockade on the Early Phase

Acute renal failure (ARF) is a common renal disease, which can be caused by an acute ischemic or toxic insult to the kidney, as well as acute obstruction of the urinary tract.4 Ischemic damage to the kidney may occur dur-ing renal hypoperfusion. However, it is the pe-riod of ischemia followed by reperfusion which

Protective Effects of Rosa Canina L Fruit Extracts on Renal

Then, the renal arteries and veins were clamped simultaneously for 30 minutes. Immediately after 30 minutes, obstruction was removed, surgical area was sutured, and the rats were returned to the cages to spend the reperfusion period. During this period, they had free access to water and food. It should also be mentioned that 100 units of heparin


lation after obstruction of thesuperior vena cava above level of the azygos vein. (/) The superior intercostal veins, other intercostal veins, and the accessory hemiazygos, hemiazygos and azygos veins form an important channel of collateral circulation. In this type of obstruction (the superior vena cava being obstructed

Collateral Circulation, Renal Function and Histology after

Collateral Circulation, Renal Function and Histology after Experimental Obstruction of Renal Veins* Sam A. Threefoot, M D., Clorinda Cabrera-Gil and James E. Pearson, Jr. Changes in renal excretion and histology were studied for varying periods fol­ lowing unilateral or bilateral ligation of the renal veins in female rats. Collaterals


Obstruction of the lymphatics and ligation of the illferior vena cava below the renal veins were performed. b) Not-ligatedgroup Only the lymphatic obstruction was undertaken. c) Control group In general, accumulation of the interstitial fluids in the media, thickening of th~ intima and degeneration of the smooth muscle cells in the aortic wall were

Postoperative venographic control following ligation of the

Experimental work in dogs, rabbits, cats, and monkeys was performed, inter alia, by PURPURA (1898), GOSSET and LECENE (1904), LEOTTA (1907), BEJAN and COHN (1911), BATSON (1940). These experiments demonstrated that ligation of the inferior vena cava, made below the renal veins, was well tolerated.

Candesartan prevents long-term impairment of renal function

Nov 06, 2017 using candesartan (CAN) on long-term renal molecular and functional changes in response to partial unilateral ureteral obstruction (PUUO). Newborn rats were subjected to severe PUUO or sham operation (SHAM) within the first 48 hr of life. CAN was provided in the drinking water (10 mg/kg/day) from day 21 of life until 10 weeks of age.

High aerobic glycolysis in renal tubular epithelial cells and

sis, glycolysis of renal tubular epithelial cell was increased, leading to the recodification of ener-gy metabolism. This process affected the num-ber and function of podocytes and aggravated renal interstitial fibrosis. Key Words: Glycolysis, Energy reprogramming, Renal tubular epithelial cells, Podocytes, Renal interstitial fibrosis

Experimental Pyelonephritis: Enhancement of Infection after

25-gauge needle, either into the renal artery or into the renal vein. Throughout the surgical pro-cedure in rats and dogs, the kidneys and ureters were not manipulated in order to avoid renal damage or urinary obstruction. Bacterial enumeration. Animals were sacri-ficed at intervals after inoculation of bacteria,

The management A - Gut

Experimental obstruction to the portal vein increased abdominal pressure acting on the renal veins may reduce renal blood flow (Bradley and Bradley, 1947).

Varicocele and left renal vein compression

cial anatomic relationships of the left renal pedi­ cle make the left renal vein (LRV) vulnerable to compression, mainly by neighboring vascular structures. Vascular variations and anomalies have been described.5-9 Some authors have men­ tioned a constant and normal arterial structure, the superior mesenteric artery (SMA), as a pos­

Maternal Venous Hemodynamic Dysfunction in Proteinuric

aspects of renal venous function and outflow. Renal congestion following venous compression, (sub)obstruction or intravenous hypertension, is a well-known cause of renal dysfunction and even failure, both in experimental and in clinical conditions. Doppler studies of the maternal venous

Efeito do sirolimo na lesão renal induzida pela ligadura do

incidence of renal dysfunction and approximately 6%-8% of patients suffer from acute renal injury, with a mortality of over 68%1,2. Causes underlying of the renal morphological and functional changes in obstructive jaundice still not been understood. To explain renal damage has been proposed the three hypotheses:


Departments of Medicine, Pathology and Experimental Pathology, Queen Elizabeth Hospital, University of Birmingham. FIFrY years ago, Rowntree, Fitz and Gerachty (1913) described the proteinuria which occurred in animals following obstruction of the inferior vena cava proximal to the renal veins or of the renal veins themselves. In the sameyear

Experimental Renal Hypertension in Dogs FORELIMB HEMODYNAMICS

obstruction of outflow through the brachial and cephalic veins; this pressure did not change and was always less than 27 mm Hg, averaging 11.4 mm Hg. Following a period of 5 10 minutes to allow the establishment of a steady state, intravascular pressures were recorded. In the six dogs that subse-quently made up the sham-operated control group

Journal of Chemical and Pharmaceutical Research, 2016, 8(8

The retro-aortic left renal vein has been studied by many authors and its prevalence is presented in Table 1. This is true for a single left renal vein passing retro-aortically. However, the incidence of 2 left renal veins, one passing anterior and other posterior to aorta i.e. renal collar or circum-aortic venous ring varies from 0.3% to 16.83

Effect of Enalapril Therapy on Glomerular Accumulation of

unilateral renal artery stenosis or ureteral ob- struction have shown that GN is less severe in the kidney with renal artery stenosis or unilateral ureteral obstruction.25 The results of previous studies also suggest that hemodynamic events induced by the renin- angiotensin system could influence glomerular

Letter to the Editor

Clinical inference of maternal renal venous Doppler ultrasonography Pregnancy is associated with maternal venous adaptations which can be assessed using venous Doppler ultrasono-graphy at the level of the renal interlobar veins (RIV). In addition to the increase in intra-abdominal interstitial pressure, with or without increased intrarenal

Inferior Vena Cava Reconstruction by Gallbladder Patch: An

Infra-renal IVC including the grafted gallbladder was harvested and the dogs were sacrificed. All the IVCs were patent (checked with an Endo Tracheal Tube NO: 8), and no sign of stricture and stenosis or obstruction and narrowing of the cava and pseudoaneurysm formation were found (Figure 2). Gross pathologic evaluations showed that the lumen

Effect ofThoracic Cava Obstruction onResponse of Proximal

obstruction. This effect is independent of change in filtration rate or renal venous pressure. Methods Studies were performed on male and female mongrel dogs weighing 10 to 25 kg. Dogs were rapidly anesthe-tized by intravenous injection of 25 mg per kg sodium *Submitted for publication August 16, 1965; accepted October 25, 1965.

Renal vascular adjustments to partial renal venous

free from surrounding tissue and renal veins with minimal disruption of the renal nerves. Electromag-netic flow probes (Statham SN-68918, Gould) cali-brated in vitro with whole blood were placed around renal arteries to measure RBF. Adjustable occluders were placed around the renal veins near the junction with the vena cava.

In -Training Test Questions Interventional Radiology

renal vascular hypertension would be fibromuscular dysplasia, the most characteristic appearance of which is a string-of-bead appearance along the course of the renal artery. B. Incorrect. Even for a 45 year-old, this is advanced atherosclerotic disease and renal failure is unusual with unilateral renal artery stenosis. Not the best choice. C

Evaluation of the Role of Ultrasound Use in the Emergency

the renal pelvis. Causes of obstruction, such as renal stones, are seen within the kidney as hyperechoic structures that result in shadowing. Additionally, the urinary bladder could be evaluated for the post-void volume in cases of distal obstruction (Labovitz et al., 2010; Jørgensen et al., 2010). DVT Ultrasound


obstruction. In these conditions there is often a quick and dramatic response to antibiotics and chemotherapy, as emphasized by Hanley (I957) in his recent review of the treatment of renal tuberculosis, and as the infection subsides the dilatation disappears. During pregnancy there is a tendency for the renal pelves and ureters to undergo hypotonic

Pancake kidney: when it is not a problem

Jan 17, 2017 renal veins (tributaries of inferior vena cava or iliac vein).9 If only single vessels are involved, the risk of compromise by pelvic trauma, pregnancy, or space occupying lesions is increased. Moreover, atherosclerosis of the aorta and iliac arteries is a hazard in old age, causing stenosis of aberrant renal arteries and possibly hypertension.

Effects of renal pelvic high-pressure perfusion on nephrons

the renal pelvic pressure is ~0.98 kPa (7.35 mmHg). In the early stage of kidney obstruction, renal blood flow perfusion increases and the renal pelvic pressure gradually increases until it reaches a maximum (8.82 kPa) (13). Following this, the renal blood flow begins to decrease, the renal glomerulus

Individual renal clearances determined at renal vein

renal pelvis. Patient 3 had unilateral hydronephrosis and a poor nephrogram on the right. A determina-tion was made whether nephrectomy would result in unacceptable loss of renal mass, or whether repair of ureteropelvic junction obstruction was indicated. In-formed consent was obtained before each procedure. Experimental. Each patient was

Influence of Renal Fluid Dynamics on Renal Lymph Pressure,

Table 1 Renal lymph to renal venous plasma concentration ratios for PAH, creatinine and protein in 5 dogs. Ratios are shown for control periods and for experimental periods (decreased renal 1 blood flow but normal IRVP). Control Experimental * p < 0.05 PAH Mean S.E. 1.64 0.19 1.28 0.14 Creatinine Protein Mean S.E. Mean S.E.

WPS Medical Policy Updates - secure.wpsic.com

stenosis) or obstruction in the portal or hepatic veins (portal venous thrombosis or Budd-Chiari syndrome) or systemic veins, such as inferior vena cava, renal veins, or iliac veins after indeterminate or equivocal ultrasound. WPS Medical Policy Updates

The Human Genome and ClinicalTrials - MedlinePlus

researchers and the public track clinical research trials of experimental treatments for many diseases and medical conditions. On pages 2-3, Dr. Francis Collins, Director of the National Institutes of Health (NIH), discusses the groundbreaking research that mapped our human genetic makeup. And he

Evolution of urological imaging

technique with an aortogram and a selective renal arterio-gram became the standard evaluation of renal masses, showing neovascularity of renal cancer and the renal arterial supply of the kidney to guide the surgeon to occlude the renal arteries before occlusion of the renal vein or veins and subsequent manipulation of the kidney for removal. Renal

0500 Intermittent Pneumatic Compression Devices (1)

Aug 11, 2020 venous wall and valves, leading to obstruction or reflux of blood flow in the veins. A systemic review of the literature concluded that the effectiveness of the addition of IPC in treatment of venous leg ulcers is unknown. The systemic review identified 3 small, randomized controlled trials (RCTs) of IPC; all of these trials were different in

Clinical Policy Bulletin: Cryoablation

malignant endobronchial obstruction), pancreatic cancer, plantar fibroma, post-infarction VT, retinopathy of prematurity, and tuberous sclerosis- associated renal angiomyolipoma experimental and investigational because its effectiveness for these indications has not been established.