Integrin α3β1–CD151 Complex Regulates Dimerization Of ErbB2 Via RhoA

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Tumorigenesis Epidermal Homeostasis and 4 in - CiteSeerX

Dirujuk 137 kali Since the discovery of the α6β4 integrin in the late 1980s, α3β1 can regulate Rac1 activity by itself via TIAM-1 (28), the.

Pancreatic cancer stem cell markers and exosomes - NET

plasma membrane via kinesin is regulated by rab25. Rab GTPase activating proteins CD151-α3β1 complex represses Slug-mediated EMT and Wnt signaling[411].

Signalling pathways linking integrins with cell cycle progression

oleh P Moreno-Layseca 2013 Dirujuk 205 kali In contrast, RhoA controls cell cycle in part via the organisation Integrin α3β1-CD151 complex regulates dimerization of ErbB2 via RhoA. Oncogene.10 halaman

CD151 regulates expression of FGFR2 in breast cancer cells

complexes with laminin-binding integrin receptors (i.e. α6β1, α3β1 Integrin alpha3beta1-CD151 complex regulates dimerization of ErbB2 via RhoA.

Tetraspanin CD9 - UTHSC Digital Commons

Activation of RhoA Restores the CD9 shRNA HAOSMC Phenotype (​HAOSMCs) does not affect CD81 or CD151 cell-surface expression. 41 these complexes illustrates how tetraspanins may regulate cellular integrin α3β1 is arguably the most characterized tetraspanin-integrin dimerization of ErbB2 via RhoA.

CD151-mediated adhesion is crucial to osteosarcoma

oleh Z Wang 2016 Dirujuk 13 kali Kusinska R, Parsons M, Odintsova E, Berditchevski. F. Integrin alpha 3 beta 1-CD151 complex regulates dimerization of ErbB2 via RhoA.

CD151 regulates expression of FGFR2 in breast - PURE

oleh R Sadej 2018 Dirujuk 5 kali Integrin alpha3beta1-. CD151 complex regulates dimerization of ErbB2 via RhoA. Oncogene 33,. 2779-2789. Robbez-Masson, L. J., Bodor, C., Jones, 

Tetraspanins and Melanoma: Role of CD63 in the - FLORE

Up-regulated expression of CRaf is seen in a subset of melanomas[46]. tetraspanin CD151 reduced integrin α6β1 dependent adhesion strengthening. A.

Physical Biology in Cancer. 5. The rocky road of metastasis

6 Nov 2013 sponse to ECM stress is largely regulated through Rho F, Parsons M. α3β1-Integrins regulate CD151 complex assembly and.

α3β1 Integrin suppresses prostate cancer metastasis via

oleh A Varzavand 2016 Dirujuk 40 kali Integrin α3β1-CD151 complex regulates dimerization of ErbB2 via RhoA. 2013. 29. Zevian SC, Johnson JL, Winterwood NE, Walters KS,  37 halaman

Tetraspanins Function as Regulators of Cellular - CORE

oleh CM Termini 2017 Dirujuk 120 kali Integrin alpha3beta1-CD151 complex regulates dimerization of. ErbB2 via RhoA. Oncogene 33, 2779 2789. doi: 10.1038/onc.2013.231.14 halaman

Valentina Iorio - The University of Liverpool Repository

oleh V Iorio 2017 Dirujuk 1 kali Through co-polymerisation, laminins organise into complex polygonal arrays on HD assembly starts with CD151 and integrin α3β1 forming the so called pre-.

Studying the impact of Tspan8 on extracellular - FreiDok plus

oleh R Khanduri 2018 6.2.1 Tspan8 regulates expression of integrins, especially α3β1 in budding from the plasma membrane via ARF6 and RHOA dependent 

Analysis of DDR1 function at epithelial cell contacts - Imperial

oleh A Cocking The activation states of Rac1 and RhoA are regulated is a strong propensity for DDR dimerization via a leucine zipper motif within the.

Original Article Expression of CD151/Tspan24 and integrin

15 Agu 2015 Expression of the CD151/alpha3beta1 complex in HER2-negative DCIS might reflect tumor complex regulates dimerization of ErbB2 via. RhoA.

α3β1 Integrin Suppresses Prostate Cancer Metastasis via

prostate cancer metastasis via depletion of a3b1 integrin, a cor- Integrin a3b1-CD151 complex regulates dimerization of ErbB2 via. RhoA.

Studies on Memo, an important ErbB2 receptor - edoc

oleh M Meira 2009 monomers occurs mainly through this dimerization arm and leads to the formation of a dimer composed of two 1:1 receptor/ligand complex (Garrett et al., 

Integrin affinity modulation and survival signalling. - Edinburgh

oleh PA Elliott 2008 affinity state whilst the sequence of amino acids distal to these regions regulate activation via interactions with inside-out signalling proteins.

Tspan8 and Tspan8/CD151 knockout mice unravel the

oleh K Zhao 2018 Dirujuk 12 kali using tumor cells, bone marrow cells (BMC) and endothelial cells (EC) elaborated Integrin α3β1-CD151 complex regulates dimerization of ErbB2 via RhoA.

Fedor Berditchevski Eric Rubinstein Editors

for a tetraspanin is difficult, since tetraspanins can regulate the surface CD151 with the laminin-binding integrin α3β1, and CD9 with the IgSF protein.

Epithelial cell migration on laminins - Universität zu Köln

oleh G Chometon-Luthe 2004 down-regulated in epithelial cells using siRNA. RhoA-deficient HaCaT cells are flat and present small focal complexes, even when plated on 

Thesis - UvA-DARE (Digital Academic Repository)

via complex formation with Miz1. J Cell. Biol 172,139-149. 93. Kurata S, et al (2004) p51/p63 controls subunit α3 of the major epidermis integrin.

The role of β1-integrin in normal and oncogene-mediated

oleh PM Layseca In contrast, RhoA controls cell cycle in part via the organisation CD151 forms a complex with α3β1 integrin, which regulates the ErbB2 

Integrin α3β1–CD151 complex regulates

oleh V Novitskaya 2014 Dirujuk 42 kali Integrin α3β1 CD151 complex regulates dimerization of ErbB2 via RhoA. V Novitskaya1,4, H Romanska2,4, R Kordek2, P Potemski2, R Kusinska2, 

SYNTHETIC PEPTIDE LIGAND MIMETICS AND TUMOR

oleh TC Sroka 2005 Figure 29: HYD1 interacts with CD151/Integrin complexes 103. Figure 30: HYD1 does not change the amount of CD151 associated with α6 

CD151 regulates expression of FGFR2 in breast cancer cells via

form complexes with laminin-binding integrin receptors (i.e. α6β1, α3β1 and α6β4​) and CD151 complex regulates dimerization of ErbB2 via RhoA. Oncogene  43 halaman

download the PDF - Open Collections - The University of

4.2.2 KAI1 Regulated HUVEC Growth through the Expression of IL-6 and VEGF For example, CD151 has been reported to interact with the α3β1 integrin.

The Context-Dependent Impact of Integrin-Associated CD151

oleh S Erfani 2021 covery of its co-translation with laminin-binding α3β1 integrin alpha3beta1-CD151 complex regulates dimerization of ErbB2 via RhoA.

Lack of CD151/integrin alpha 3 beta 1 complex is predictive of

oleh HM Romanska 2015 Dirujuk 20 kali CD151/integrin α3β1 complex in patients with HER2-negative tumours. CD151 might contribute to mammary tumourigenesis via ErbB2/HER2 (Deng et al., 2012;.

A Dissertation entitled Cytotoxic peptides targeting sGCα1 and

oleh J Zhou 2017 designed peptides to target an AR-regulated gene, soluble guanylyl interacts with Integrin, including α3β1 and α6β4106,109, and non-Integrin proteins,.

Załącznik 2 - Gdański Uniwersytet Medyczny

oleh R Sądej Berditchevski F. CD151 regulates tumourigenesis by modulating the Berditchevski, Integrin α3β1-CD151 complex regulates dimerization of ErbB2 via RhoA, 

Etude du rôle des intégrines liant la laminine - TEL (thèses

oleh S Cagnet 2013 (iii) the α3β1 integrin plays a major role in mammary tumorigenesis, it promotes survival La protéine FAK, via les petites GTPases RhoA,.

Absence of integrin α3β1 promotes the progression of HER2

oleh V Ramovs 2019 Dirujuk 8 kali Keywords: Integrin α3β1, HER2, MMTV-cNeu, Metastasis, Breast cancer, Integrin α3β1-CD151 complex regulates dimerization of ErbB2 via. RhoA. Oncogene.17 halaman

Identification of novel targets in fibrosis - UCL Discovery

oleh J Verneau 2018 TSPAN13 was found up-regulated in fibrosis and appears to be a potent The force exerted by stress fibers through transmembrane integrins can activate.

Structural Studies of Two Cancer Targets Involved in Protein

oleh WKJ Tang 2017 CD151 EC2 dimers and proteolytic products was performed with Dr. David Ascher of CD151 interacts directly with integrins α3β1 and α6β1 and it is.

The Tetraspanin CD151 in Papillomavirus Infection - Semantic

oleh KD Scheffer Dirujuk 39 kali One of the putative candidates is the α6 integrin complex F. Integrin α3β1-CD151 complex regulates dimerization of ErbB2 via RhoA.

Analysis of Integrin α6β4 Function in Breast Carcinoma

oleh KD Gerson 2012 β4-regulated mRNAs are enriched in putative targets of miRNA families. Chapter III. Figure 3.1 β4 integrin regulates expression of SPARC.

Tetraspanins as regulators of the tumour microenvironment

oleh S Detchokul 2014 Dirujuk 75 kali complex of integrins, signalling proteins and actin cytoskel- tetraspanin-partner interactions, such as CD151-α3β1 integ-.

Cell-Surface Association between Progelatinases and - Helda

oleh M STEFANIDAKIS 2006 BLOCKING THE PROGELATINASE/β2 INTEGRIN COMPLEX INHIBITS MIGRATION OF PMNs TO RhoA controls focal adhesion formation and actomyocin-mediated contraction 

CD151 promotes α3β1 integrin-dependent organization of

oleh SC Zevian 2015 Dirujuk 17 kali carcinoma cell junctions via a3b1 integrin, by a mechanism that requires the a3b1 ligand, laminin-332. Loss of CD151.

Załącznik 2 Autoreferat w języku polskim - Wydział Lekarski

Odintsova E, Berditchevski F. Integrin α3β1-CD151 complex regulates dimerization of. ErbB2 via RhoA. Oncogene. 2014; 33(21):2779-89. (*equal contribution).

Deciphering the Mammary Stem Cell Niche - ScienceDirect.com

oleh M Romagnoli 2019 Dirujuk 13 kali dimers α3β1, α6β1 and α6β4 are expressed by mammary basal epithelial cells Integrin alpha3beta1-CD151 complex regulates dimerization of ErbB2 via RhoA.

Chapter 2 - Scholarly Publications Leiden University

oleh V Ramovš 2021 the laminin-binding integrins α3β1 and α6β4 in tumor development and Integrin α3β1-CD151 complex regulates dimerization of ErbB2 via RhoA, Oncogene.

Cover Page The handle https://hdl.handle.net/1887/3147161

oleh L Molder 2021 Berditchevski, Integrin α3β1-CD151 complex regulates dimerization of ErbB2 via RhoA, Oncogene. 33 (2014) 2779 2789. https://doi.org/10.1038/onc.2013.231.

Grade Serous Ovarian Cancer - TSpace - University of Toronto

CD151 differentially regulates cell survival and migration of HGSC cell site on CD151 are unable to recognize CD151 in complex with α3β1, 

The epithelial cell adhesion molecule (EpCAM) regulates cell

19 Sep 2012 the cadherin/β-catenin complex to actin via its ability to bind associated with integrin α3β1, was shown to regulate epithelial 

CD151 drives cancer progression depending on integrin α3β1

oleh J Zhu 2021 pathways via activation of EGFR/ErbB2 in NSCLC cells. Integrin α3β1-CD151 complex regulates dimerization of ErbB2 via. RhoA. Oncogene.18 halaman

Use of tetraspanins CD151 and CD9 as biomarkers for breast

oleh D Bond 2014 Res. 7(6), 787 798 (2009). 11 Novitskaya V, Romanska H, Kordek R et al. Integrin α3βa1 CD151 complex regulates dimerization of ErbB2 via RhoA. Oncogene.

Clarke, Cassie J. (2015) An investigation into the role of the

oleh CJ Clarke 2015 increase cell migration depended on the ability of integrin α5β1 to bind its The FN dimer forms through C terminal disulphide bonds,.

Cell Adhesion in Cancer - Hindawi.com

21 Nov 2011 tumors by regulating cell adhesion status using ECM-derived Similarly, the suppression of integrin α3β1 in breast cancer.