Tofacitinib Safe And Effective In Renal Transplant Recipients
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Are calcineurin inhibitors-free regimens ready for prime time?
provide safe and effective immunosuppression without renal or cardiovascular toxicities. The approval of belatacept in both the United States and Europe for use in renal transplantation will finally push CNI-free regimens into prime time. Novel biologics such as ASKP1240 (a human anti-CD40 monoclonal antibody) and one small molecule, tofacitinib,
W J T World Journal of Transplantation
munosuppression is effective and safe treatment of trastaurin and tofacitinib. The purpose of this review is agents in renal transplant recipients.
IMURAN (azathioprine) 50-mg Scored Tablets PRODUCT
Post-transplant. Renal transplant patients are known to have an increased risk of malignancy, predominantly skin cancer and reticulum cell or lymphomatous tumors. The risk of post-transplant lymphomas may be increased in patients who receive aggressive treatment with immunosuppressive drugs, including IMURAN.
REVIEW Open Access Phospho-specific flow cytometry for
is a safe and effective immunosuppressant leading to sig-nificantly better renal function (GFR, glomerular filtra-tion rate) as compared to a cyclosporine-based regimen in kidney transplant recipients [8-10]. Acute rejection rates were higher but clinically acceptable among belatacept-treated patients (17-22% at 12 months in the
Dept of Transplantation Medicine and Nephrology, Warsaw
Effective and safe GS withradawal in patients Worsening of native kidneys function at recipients of non-renal organs Transplant Int, 2010, 23, 761