Prediction Of Antidepressant Response To Milnacipran By Norepinephrine Transporter Gene Polymorphisms
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The aim of the present study is to predict responders to serotonin noradrenaline better response to milnacipran, a serotonin-noradrenaline reuptake.
Norepinephrine transporter function and human
28 Sep 2012 Studies in patients with the postural tachycardia syndrome (POTS) suggest that changes in NET function can occur through genetic mecha- nisms.
Therapy response prediction in major depressive disorder
by A Shalimova 2021 Tricyclic antidepressants: genetic polymorphisms of functional importance and response to milnacipran by norepinephrine transporter gene.
The pharmacogenetics of antidepressant treatments for
on the association between antidepressant responses and genetic polymorphisms, including in the serotonin transporter, tryptophan hydroxylase,
Milnacipran, a serotonin and norepinephrine reuptake inhibitor
The development of antidepressants such as the serotonin norepinephrine reuptake inhibitors. (SNRIs), for example, duloxetine (Cymbalta®,. Eli Lilly and Company
Monoamine Transporter Gene Polymorphisms and
2006 Cited by 239 Monoamine Transporter Gene Polymorphisms and Antidepressant Response in Koreans. With Late-Life Depression. Hyeran Kim, MD. Shinn-Won Lim, MS.
Pharmacogenetics from ethno-cultural perspectives
by C Ng Advances in genetic technology have focussed on how genetic polymorphisms may impact on drug metabolism, response, adverse effects and clinical outcome.
Concepts in Pharmacogenomics - Sample Chapter 5 - ASHP
68. Yoshida K, Takahashi H, Higuchi H, et al. Prediction of antidepressant response to milnacipran by norepinephrine transporter gene polymorphisms.
Possibility of Predicting Serotonin Transporter Occupancy
by M Yahata 2017 Cited by 1 norepinephrine by both SERTs and norepinephrine transporters in gene ABCB1 predict antidepressant treatment response in depression.
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by A Drago Cited by 59 (2004), 'Prediction of anti- depressant response to milnacipran by norepinephrine transporter gene polymorphisms', Am. J. Psychiatry Vol. 161, pp.
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by L Yin 2015 Cited by 10 and gene polymorphisms predicted 74.8 % of response to milnacipran by norepinephrine transporter gene poly- morphisms.
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4 Sep 2018 genes and polymorphisms is weak, therefore gene x gene interactions or Encodes noradrenaline transporter reuptaking neurotransmission of.
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by S Porcelli 2012 Cited by 320 In the last decade the serotonin transporter gene promoter polymorphism the most studied genetic variant as predictor of antidepressant response.
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by C Mora Cited by 24 blood-based biomarkers associated with antidepressant treatment response with including polymorphisms, gene expression (mRNA levels), epigenetics,
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by W Marsh 2006 66. Yoshida K, Takahashi H, Higuchi H et al. Prediction of antidepressant response to milnacipran by norepinephrine transporter gene polymorphisms.
Prediction of Antidepressant Response to Milnacipran by - FOCUS
gene (NET) and serotonin transporter gene (5-HTT) polymorphisms are associated with milnacipran, a dual serotonin/ norepinephrine reuptake inhibitor. part determine the antidepressant response to milnacipran. Prediction of antide-.
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by P Vizeli 2018 Cited by 11 Conclusions Genetic polymorphisms of the SLC6A2 gene weakly moderated the acute (2004) Prediction of antidepressant response to milnacipran by nor-.
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by B Deakin 2001 Cited by 2 biological markers or genetic polymorphisms, the identification of venlafaxine and milnacipran are new combined noradrenaline and serotonin uptake.
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by I Ueda 2016 Cited by 16 Earlier studies implicated norepinephrine transporter (NET) gene (SLC6A2) polymorphisms in the etiology of major depressive disorder (MDD).
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by T Linka 2009 Prediction of antidepressant response to milnacipran by norepinephrine transporter gene polymorphisms. Am J Psychiatry 2004;. 161:1575-1580.
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by J Kirchheiner 2007 Cited by 106 dopamine transporter (DAT1) gene and the Keywords: response prediction; antidepressant drug response; SSRI; pharmacogenetics;.
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by T Higuchi 2007 Cited by 6 In contrast, the presence of the 5-HT transporter gene polymorphisms, 5HTTLPR and 5HTTVNTR, had no effect on the antidepressant response to milnacipran.
Pharmacogenomics - RACGP
remains little changed.2 Genetic prediction of antidepressant response has potential to norepinephrine transporter gene NET polymorphisms may.
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2018 Cited by 545 As explained below in more detail, genetic polymorphisms predict clinical efficacy and/or tolerability of antidepressants in hu-.
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by C Fabbri 2014 Cited by 66 141. Yoshida K, Takahashi H, Higuchi H, et al. Prediction of antidepressant response to milnacipran by norepinephrine transporter gene polymorphisms.
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by S Porcelli 2011 Cited by 177 185. Yoshida K, Takahashi H, Higuchi H, et al. Prediction of anti - depressant response to milnacipran by norepinephrine transporter gene polymorphisms.
Serotonin Transporter Gene Polymorphism Associated with
by SH Lee 2010 Cited by 31 rotonin transporter polymorphisms. No influence of 5-. HTTLPR polymorphisms on the antidepressant response to milnacipran was detected.
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by C Crisafulli Cited by 109 norepinephrine transporter, the dopamine transporter, variants in the 5- Keywords: pharmacogenetics, antidepressants, gene, SNP, depression.
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by MJ Arranz 2008 Cited by 115 ulocytosis, hyperlipidemia, and response to antipsychotic and antidepressant medications. While these tests based on mul- tiple genes show
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by K Yoshida 2008 Cited by 64 the COMT val158met polymorphism and the antidepressant response to serotonin noradrenaline reuptake inhibitors (SNRIs), although noradrenergic genetic
Personalized assessment and treatment of depression
by AJ Fisher 2015 Cited by 23 the rs806368 polymorphism of the CNR1 gene predicted citalopram response, with G mune systems together predicted antidepressant response.
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by A Serretti 2007 Cited by 7 polymorphism and response to Selective Serotonin. Reuptake Inhibitors (SSRIs). transporter gene predicts non-remission in major depression.
Are there meaningful biomarkers of treatment response for
by B Breitenstein 2014 Cited by 66 antidepressant response with a focus on drug delivery across the blood brain barrier and predicted by genetic polymorphisms in ABCB1 [16 25]. The first.
by A Serretti 2004 Cited by 7 Key Words: Pharmacogenetics Antidepressant response Major depression SSRI (if the polymorphism is located in a gene promoter).
Pharmacogenetics and Analgesic Effects of - MD Labs
by F Rodieux 2015 Cited by 6 The impacts of genetic polymorphisms in the targets of antidepressants, such as the serotonin receptor or transporter, the noradrenaline transporter and the
Clinical Implementation of Pharmacogenetic Decision Support
by Z Zeier Cited by 69 tions have been devoted to identifying gene-drug interac- tions that affect the response to antidepressant medications by modulating their pharmacokinetic
Effects of Persisting Emotional Impact from Child Abuse and
by AB Singh Cited by 7 Polymorphisms of the norepinephrine transporter (NET) may also be involved. Prediction of antidepressant response has been an elu-.
Analysis of Association between Norepinephrine Transporter Gene
Key Wordsaa Norepinephrine transporter, Gene polymorphism, NEO-FFI, Personality. Received: polymorphisms affect susceptibility to depression and predict antide- diction of antidepressant response to milnacipran by norepinephrine.
Genetic variants in combination with early partial - Nature
by M Kato 2015 Cited by 15 if their contributions to antidepressant response were significant in those studies.5,6,14-17 In detail, serotonin transporter (SLC6A4) gene
Personalized medicine in psychiatry: problems and promises
by U Ozomaro 2013 Cited by 216 T, Itoh K, Inoue K, Suzuki T, Nemeroff CB: Prediction of antidepressant response to milnacipran by norepinephrine transporter gene polymorphisms.
Moving pharmacoepigenetics tools for depression toward
by LM Hack 2019 Cited by 15 predict antidepressant response as part of the field of monoaminergic transporter genes have been tested with respect to baseline epigenetic status.
Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4
by C Dong 2009 Cited by 170 dopamine, and serotonin transporters (SLC6A2, SLC6A3 and SLC6A4), Keywords: nucleotide polymorphism; antidepressant response;
Norepinephrine and Serotonin Transporter Genes - Karger
by A Baffa 2010 Cited by 79 NET gene, as well as serotonin-transporter-linked promoter antidepressant treatment response in major depression.