Modulation Of Human Neutrophil Functions In Vitro By Treponema Denticola Major Outer Sheath Protein

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Induction of De Novo Subcortical Actin Filament Assembly by

Among T. denticola s putative virulence factors, its major outer sheath protein (Msp) has achieved notoriety for its im-munogenicity, its ability to bind human matrix proteins, its pore-forming capacity, and its toxicity for some types of human cells in culture (3 6). Our laboratory has recently reported two

Modulation of Human Neutrophil Functions In Vitro by

Modulation of Human Neutrophil Functions In Vitro by Treponema denticola Major Outer Sheath Protein Bina Puthengady Thomas, Chun Xiang Sun, Elena Bajenova, Richard P. Ellen,† and Michael Glogauer†* CIHR Group in Matrix Dynamics and Dental Research Institute, Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada